| month | day | visitor | score | home | score |
|---|
| November | 2, 2024 | Pistons | 122 | Magic | 113 |
| November | 3, 2024 | Nets | 102 | Pistons | 99 |
| November | 7, 2024 | Pistons | 102 | Celtics | 88 |
| November | 9, 2024 | Hawks | 96 | Pistons | 123 |
| November | 11, 2024 | Wizards | 104 | Pistons | 108 |
| November | 16, 2024 | Pistons | 128 | Wizards | 109 |
| November | 18, 2024 | Bucks | 104 | Pistons | 125 |
| November | 23, 2024 | Pistons | 100 | Pacers | 90 |
| November | 24, 2024 | Hornets | 95 | Pistons | 115 |
| November | 25, 2024 | Pistons | 88 | Grizzlies | 85 |
| November | 26, 2024 | Pistons | 101 | Celtics | 80 |
| December | 2, 2024 | Pistons | 107 | Nets | 120 |
| December | 3, 2024 | Pistons | 116 | Suns | 107 |
| December | 7, 2024 | Bucks | 124 | Pistons | 104 |
| December | 8, 2024 | Pistons | 98 | Hornets | 73 |
| December | 11, 2024 | Thunder | 100 | Pistons | 93 |
| December | 12, 2024 | Pistons | 105 | Hawks | 97 |
| December | 15, 2024 | Pistons | 97 | 76ers | 140 |
| December | 18, 2024 | Pistons | 122 | Nuggets | 110 |
| December | 19, 2024 | Pistons | 84 | Jazz | 69 |
| December | 24, 2024 | Pistons | 104 | 76ers | 124 |
| December | 25, 2024 | 76ers | 121 | Pistons | 104 |
| December | 29, 2024 | Warriors | | Pistons | |
| December | 31, 2024 | Bulls | | Pistons | |
| January | 3, 2025 | Wolves | | Pistons | |
| January | 9, 2025 | Pistons | | Hornets | |
| January | 10, 2025 | Pacers | | Pistons | |
| January | 12, 2025 | Pistons | | Hawks | |
| January | 16, 2025 | Pistons | | Magic | |
| January | 17, 2025 | Jazz | | Pistons | |
| January | 18, 2025 | Kings | | Pistons | |
| January | 19, 2025 | Pistons | | Raptors | |
| January | 20, 2025 | Pistons | | Heat | |
| January | 22, 2025 | Magic | | Pistons | |
| January | 23, 2025 | Pistons | | Pelicans | |
| January | 25, 2025 | Bucks | | Pistons | |
| January | 28, 2025 | Clippers | | Pistons | |
| January | 29, 2025 | Raptors | | Pistons | |
| January | 30, 2025 | Knicks | | Pistons | |
| February | 1, 2025 | Pistons | | Bulls | |
| February | 4, 2025 | Pistons | | Raptors | |
| February | 6, 2025 | Pistons | | Cavaliers | |
| February | 7, 2025 | Cavaliers | | Pistons | |
| February | 8, 2025 | Blazers | | Pistons | |
| February | 13, 2025 | Hornets | | Pistons | |
| February | 15, 2025 | Pelicans | | Pistons | |
| February | 17, 2025 | Spurs | | Pistons | |
| February | 18, 2025 | Pistons | | Lakers | |
| February | 20, 2025 | Pistons | | Heat | |
| February | 21, 2025 | Pistons | | Clippers | |
| February | 22, 2025 | Bulls | | Pistons | |
| February | 27, 2025 | Pistons | | Spurs | |
| February | 28, 2025 | Pistons | | Bulls | |
| March | 2, 2025 | Pistons | | Hornets | |
| March | 5, 2025 | Pistons | | Rockets | |
| March | 8, 2025 | Suns | | Pistons | |
| March | 10, 2025 | Pistons | | Cavaliers | |
| March | 11, 2025 | Pistons | | Knicks | |
| March | 12, 2025 | Cavaliers | | Pistons | |
| March | 14, 2025 | Lakers | | Pistons | |
| March | 15, 2025 | Mavericks | | Pistons | |
| March | 22, 2025 | Pistons | | Bucks | |
| March | 23, 2025 | Grizzlies | | Pistons | |
| March | 27, 2025 | Pistons | | Knicks | |
| March | 29, 2025 | Pacers | | Pistons | |
| March | 31, 2025 | Pistons | | Wolves | |
| April | 1, 2025 | Heat | | Pistons | |
| April | 3, 2025 | Hawks | | Pistons | |
| April | 4, 2025 | Bulls | | Pistons | |
| April | 5, 2025 | Hawks | | Pistons | |
| April | 6, 2025 | Pistons | | Thunder | |
| April | 7, 2025 | Raptors | | Pistons | |
| April | 9, 2025 | Pistons | | Blazers | |
| April | 10, 2025 | Pistons | | Kings | |
| April | 11, 2025 | Nuggets | | Pistons | |
| April | 13, 2025 | Pistons | | Mavericks | |
| April | 14, 2025 | Pistons | | Pacers | |
| April | 17, 2025 | Pistons | | Bucks | |
| April | 20, 2025 | Rockets | | Pistons | |
| April | 22, 2025 | Nets | | Pistons | |
| April | 25, 2025 | Wizards | | Pistons | |
| April | 27, 2025 | Cavaliers | | Pistons | |
| April | 29, 2025 | Celtics | | Pistons | |
| May | 4, 2025 | Pistons | | Warriors | |